Genetic selection of low fertile Onchocerca volvulus by ivermectin treatment.

• Main Authors: Catherine Bourguinat (Author), Sébastien D S Pion (Author), Joseph Kamgno (Author), Jacques Gardon (Author), Brian O L Duke (Author), Michel Boussinesq (Author), Roger K Prichard (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Onchocerca volvulus is the causative agent of onchocerciasis, or "river blindness". Ivermectin has been used for mass treatment of onchocerciasis for up to 18 years, and recently there have been reports of poor parasitological responses to the drug. Should ivermectin resistance...