Effectiveness and Safety of the Coadministration of Rifampin and Warfarin versus Direct Oral Anticoagulants: A Cohort Study

• Main Authors: Ju-Chieh Wung (Author), Chia-Chen Hsu (Author), Chi-En Wang (Author), Yaa-Hui Dong (Author), Chia-Chieh Lin (Author), Szu-Yu Wang (Author), Shih-Lin Chang (Author), Yuh-Lih Chang (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Pharmacokinetic studies have shown that rifampin reduces the levels of oral anticoagulants during the initiation of coadministration, raising concerns about an increased thrombotic risk, but there are limited comparative clinical outcomes between rifampin and warfarin compared with dir...