A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood

• Main Authors: Anne E. Turco (Author), Steven R. Oakes (Author), Kimberly P. Keil Stietz (Author), Cheryl L. Dunham (Author), Diya B. Joseph (Author), Thrishna S. Chathurvedula (Author), Nicholas M. Girardi (Author), Andrew J. Schneider (Author), Joseph Gawdzik (Author), Celeste M. Sheftel (Author), Peiqing Wang (Author), Zunyi Wang (Author), Dale E. Bjorling (Author), William A. Ricke (Author), Weiping Tang (Author), Laura L. Hernandez (Author), Janet R. Keast (Author), Adrian D. Bonev (Author), Matthew D. Grimes (Author), Douglas W. Strand (Author), Nathan R. Tykocki (Author), Robyn L. Tanguay (Author), Richard E. Peterson (Author), Chad M. Vezina (Author)
• Format: Book
• Published: The Company of Biologists, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Benign prostatic hyperplasia/lower urinary tract dysfunction (LUTD) affects nearly all men. Symptoms typically present in the fifth or sixth decade and progressively worsen over the remainder of life. Here, we identify a surprising origin of this disease that traces back to the intrauterine environm...