The Pyrazolone Originally Reported to Be a Formyl Peptide Receptor (FPR) 2/ALX-Selective Agonist Is Instead an FPR1 and FPR2/ALX Dual Agonist

• Main Authors: Yoshitaka Sogawa (Author), Akiko Shimizugawa (Author), Takao Ohyama (Author), Hiroaki Maeda (Author), Kazuki Hirahara (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A pyrazolone compound acting as a formyl peptide receptor (FPR) 2/ALX-selective agonist has been reported, but its pharmacological activities on human FPRs (hFPRs) and mouse FPRs (mFprs) have not been well demonstrated. In this study, we found that this compound, designated as compound A, induced co...