Dysregulation and detection methods of EGFR in oral cancer. A narrative review.

• Main Authors: Carolina Somarriva (Author), Alejandra Fernández (Author), Jorge Candia (Author), Javier Campos (Author), Daniela Albers (Author), Jorge Briceño (Author)
• Formato: Libro
• Publicado: Universidad de Concepción., 2016-11-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein, with an intracellular domain and tyrosine kinase function (TK) involved in cell proliferation. Dysfunctions in EGFR signaling pathways have been associated with oral malignant tumors such as oral squamous cell carcinoma (OSCC)....