An Integrated Approach Based on Network Analysis Combined With Experimental Verification Reveals PI3K/Akt/Nrf2 Signaling Is an Important Way for the Anti-Myocardial Ischemia Activity of Yi-Qi-Tong-Luo Capsule

• Egile Nagusiak: Huxinyue Duan (Egilea), Meiyan Li (Egilea), Jia Liu (Egilea), Jiayi Sun (Egilea), Chunjie Wu (Egilea), Yu Chen (Egilea), Xiaohui Guo (Egilea), Xinglong Liu (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background:Yiqi-Tongluo Capsule (YTC) is a Chinese traditional patent medicine that has been used in the treatment of myocardial ischemia (MI). However, its molecular mechanisms against MI have not been clear.Methods: Network analysis and experimental verification were used to explore the potential...