PPARα Ameliorates Doxorubicin-Induced Cardiotoxicity by Reducing Mitochondria-Dependent Apoptosis via Regulating MEOX1

• Principais autores: Wei Wang (Autor), Qin Fang (Autor), Zhihao Zhang (Autor), Daowen Wang (Autor), Lujin Wu (Autor), Yan Wang (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Doxorubicin (DOX), a chemotherapeutic drug widely used in the clinical setting, is known to cause serious cardiotoxicity and greatly reduces the survival rate as well as quality of life of patients receiving chemotherapy. Peroxisome proliferation activated receptor α (PPARα) is a type of ligand acti...