ABT-333 (Dasabuvir) Increases Action Potential Duration and Provokes Early Afterdepolarizations in Canine Left Ventricular Cells via Inhibition of I<sub>Kr</sub>
ABT-333 (dasabuvir) is an antiviral agent used in hepatitis C treatment. The molecule, similarly to some inhibitors of hERG channels, responsible for the delayed rectifier potassium current (I<sub>Kr</sub>), contains the methanesulfonamide group. Reduced I<sub>Kr</sub> curren...
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MDPI AG,
2023-03-01T00:00:00Z.
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