ABT-333 (Dasabuvir) Increases Action Potential Duration and Provokes Early Afterdepolarizations in Canine Left Ventricular Cells via Inhibition of I_Kr

• Asıl Yazarlar: Zsigmond Máté Kovács (Yazar), József Óvári (Yazar), Csaba Dienes (Yazar), János Magyar (Yazar), Tamás Bányász (Yazar), Péter P. Nánási (Yazar), Balázs Horváth (Yazar), Adam Feher (Yazar), Zoltan Varga (Yazar), Norbert Szentandrássy (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

ABT-333 (dasabuvir) is an antiviral agent used in hepatitis C treatment. The molecule, similarly to some inhibitors of hERG channels, responsible for the delayed rectifier potassium current (I_Kr), contains the methanesulfonamide group. Reduced I_Kr curren...