Comparison of Immunohistochemical and Fluorescence In Situ Hybridization Assessment for HER-2/neu Status in Taiwanese Breast Cancer Patients

• Main Authors: Shou-Jen Kuo (Author), Boris Bao-Tyan Wang (Author), Cheng-Shyong Chang (Author), Tze-Ho Chen (Author), Kun-Tu Yeh (Author), Dong-Jay Lee (Author), Pao-Lun Yin (Author), Ming Chen (Author)
• Format: Book
• Published: Elsevier, 2007-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Accurate diagnostic assessment of human epidermal growth factor receptor-2 (HER-2) is essential and a prerequisite for appropriate application of the humanized anti-HER-2 monoclonal antibody trastuzumab (Herceptin) to the treatment of patients with breast cancer. Immunohistochemistry (IHC...