PM2.5 exposure and DLEC1 promoter methylation in Taiwan Biobank participants

• Main Authors: Ying-Hsiang Chou (Author), Disline Manli Tantoh (Author), Ming-Chi Wu (Author), Yeu-Sheng Tyan (Author), Pei-Hsin Chen (Author), Oswald Ndi Nfor (Author), Shu-Yi Hsu (Author), Chao-Yu Shen (Author), Chien-Ning Huang (Author), Yung-Po Liaw (Author)
• Format: Book
• Published: Komiyama Printing Co. Ltd, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Particulate matter (PM) < 2.5 μm (PM2.5) or fine PM is a serious public health concern. It affects DNA methylation and heightens carcinogenesis. Deleted in lung and esophageal cancer 1 (DLEC1) is a tumor suppressor gene. However, aberrant methylation of the gene is associated...