Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis

• Main Authors: Junmin Zhang (Author), Zai-Qin Zheng (Author), Qianhe Xu (Author), Ya Li (Author), Kun Gao (Author), Jianguo Fang (Author)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Isolation and identification of natural products from plants is an essential approach for discovering drug candidates. Herein we report the characterization of three sesquiterpene lactones from a new genus Shangwua, e.g. onopordopicrin (ONP), C2, and C3, and evaluation of their pharmacological funct...