Non-Mitogenic Fibroblast Growth Factor 1 Enhanced Angiogenesis Following Ischemic Stroke by Regulating the Sphingosine-1-Phosphate 1 Pathway

• Main Authors: Yuchi Zou (Author), Jian Hu (Author), Wenting Huang (Author), Shasha Ye (Author), Fanyi Han (Author), Jingting Du (Author), Mingjie Shao (Author), Ruili Guo (Author), Jingjing Lin (Author), Yeli Zhao (Author), Ye Xiong (Author), Xue Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemic strokes account for about 80% of all strokes and are associated with a high risk of mortality. Angiogenesis of brain microvascular endothelial cells may contribute to functional restoration following ischemia. Fibroblast growth factor 1 (FGF1), a member of FGF superfamily, involved in embry...