Activation studies with amines and amino acids of the β-carbonic anhydrase encoded by the Rv3273 gene from the pathogenic bacterium Mycobacterium tuberculosis

• मुख्य लेखकों: Andrea Angeli (लेखक), Sonia Del Prete (लेखक), Sameh M. Osman (लेखक), Fatmah A. S. Alasmary (लेखक), Zeid AlOthman (लेखक), William A. Donald (लेखक), Clemente Capasso (लेखक), Claudiu T. Supuran (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The activation of a β-class carbonic anhydrase (CAs, EC 4.2.1.1) from Mycobacterium tuberculosis, encoded by the gene Rv3273 (mtCA 3), was investigated using a panel of natural and non-natural amino acids and amines. mtCA 3 was effectively activated by D-DOPA, L-Trp, dopamine and serotonin, with KAs...