A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables

• Автори: Yu Fu (Автор), Hadi Taghvafard (Автор), Medhat M. Said (Автор), Eric I. Rossman (Автор), Teresa A. Collins (Автор), Stéphanie Billiald‐Desquand (Автор), Derek Leishman (Автор), Piet H. van derGraaf (Автор), J. G. Coen vanHasselt (Автор), Nelleke Snelder (Автор)
• Формат: Книга
• Опубліковано: Wiley, 2022-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract The use of systems‐based pharmacological modeling approaches to characterize mode‐of‐action and concentration‐effect relationships for drugs on specific hemodynamic variables has been demonstrated. Here, we (i) expand a previously developed hemodynamic system model through integration of ca...