Inhibition of p38 mitogen-activated protein kinase exerts a hypoglycemic effect by improving β cell function via inhibition of β cell apoptosis in db/db mice

• Egile Nagusiak: Xiaowei Wei (Egilea), Nan Gu (Egilea), Nan Feng (Egilea), Xiaohui Guo (Egilea), Xiaowei Ma (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The p38 mitogen-activated protein kinase (MAPK) pathway is involved in endoplasmic reticulum stress (ERS) and inflammation, which may play an important role in the pathogenesis of type 2 diabetes (T2DM). This study aimed to investigate whether p38 MAPK contributes to the pathogenesis of T2DM. 6-week...