Spectroscopic and thermodynamic characterization of the interaction of a new synthesized antitumor drug candidate 2H4MBBH with human serum albumin

• Κύριοι συγγραφείς: Silviya Abarova (Συγγραφέας), Katerina Stoitchkova (Συγγραφέας), Svetlin Tzonev (Συγγραφέας), Maria Argirova (Συγγραφέας), Denitsa Yancheva (Συγγραφέας), Neda Anastassova (Συγγραφέας), Boris Tenchov (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Pensoft Publishers, 2024-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

In the present work we studied the interactions of a newly synthesized drug candidate, 2-(2-hydroxy-4-methoxybenzylidene)-1-(1H-benzimidazol-2-yl)hydrazine (2H4MBBH), with human serum albumin (HSA) by fluorescence spectroscopy. 2H4MBBH-HSA binding parameters were assessed by fluorescence quenching s...