Spectroscopic and thermodynamic characterization of the interaction of a new synthesized antitumor drug candidate 2H4MBBH with human serum albumin

• 主要な著者: Silviya Abarova (著者), Katerina Stoitchkova (著者), Svetlin Tzonev (著者), Maria Argirova (著者), Denitsa Yancheva (著者), Neda Anastassova (著者), Boris Tenchov (著者)
• フォーマット: 図書
• 出版事項: Pensoft Publishers, 2024-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In the present work we studied the interactions of a newly synthesized drug candidate, 2-(2-hydroxy-4-methoxybenzylidene)-1-(1H-benzimidazol-2-yl)hydrazine (2H4MBBH), with human serum albumin (HSA) by fluorescence spectroscopy. 2H4MBBH-HSA binding parameters were assessed by fluorescence quenching s...