Colon Drug Delivery Systems Based on Swellable and Microbially Degradable High-Methoxyl Pectin: Coating Process and In Vitro Performance

• Main Authors: Saliha Moutaharrik (Author), Luca Palugan (Author), Matteo Cerea (Author), Gabriele Meroni (Author), Eleonora Casagni (Author), Gabriella Roda (Author), Piera Anna Martino (Author), Andrea Gazzaniga (Author), Alessandra Maroni (Author), Anastasia Foppoli (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oral colon delivery systems based on a dual targeting strategy, harnessing time- and microbiota-dependent release mechanisms, were designed in the form of a drug-containing core, a swellable/biodegradable polysaccharide inner layer and a gastroresistant outer film. High-methoxyl pectin was employed...