The RASopathies: from pathogenetics to therapeutics

• Huvudskapare: Katie E. Hebron (Författare, medförfattare), Edjay Ralph Hernandez (Författare, medförfattare), Marielle E. Yohe (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: The Company of Biologists, 2022-02-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

The RASopathies are a group of disorders caused by a germline mutation in one of the genes encoding a component of the RAS/MAPK pathway. These disorders, including neurofibromatosis type 1, Noonan syndrome, cardiofaciocutaneous syndrome, Costello syndrome and Legius syndrome, among others, have over...