The Evaluation of Pharmacodynamics and Pharmacokinetics of Anti-thrombin DNA Aptamer RA-36

• Main Authors: Elena Zavyalova (Author), Nadezhda Samoylenkova (Author), Alexander Revishchin (Author), Askar Turashev (Author), Ilya Gordeychuk (Author), Andrey Golovin (Author), Alexey Kopylov (Author), Galina Pavlova (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anticoagulants are a vital class of drugs, which are applied for short-term surgical procedures, and for long-term treatments for thrombosis prevention in high risk groups. Several anticoagulant drugs are commercially available, but all have intrinsic disadvantages, e.g., bleeding risks, as well as...