Decreased expression of hepatic glucokinase in type 2 diabetes

• Главные авторы: Rebecca A. Haeusler (Автор), Stefania Camastra (Автор), Brenno Astiarraga (Автор), Monica Nannipieri (Автор), Marco Anselmino (Автор), Ele Ferrannini (Автор)
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• Опубликовано: Elsevier, 2015-03-01T00:00:00Z.
• Предметы: article
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Background/objectives: Increased endogenous glucose production is a hallmark of type 2 diabetes. Evidence from animal models has suggested that a likely cause of this is increased mRNA expression of glucose 6-phosphatase and phosphoenolpyruvate carboxykinase (encoded by G6PC, PCK1 and PCK2). But ano...