Butyrate suppresses abnormal proliferation in colonic epithelial cells under diabetic state by targeting HMGB1

• Main Authors: Si-Yi Wang (Author), Jie-Yao Li (Author), Ji-Hao Xu (Author), Zhong-Sheng Xia (Author), Di Cheng (Author), Wa Zhong (Author), Yu Lai (Author), Tao Yu (Author), Qi-Kui Chen (Author)
• Format: Book
• Published: Elsevier, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Butyrate is widely accepted as a proliferation inhibitor in colon cancer but less thoroughly characterized in the colonic epithelium of objects with type 2 diabetes mellitus. The present study investigated the regulatory effect of butyrate on proliferation, the related molecule high-mobility group b...