DJ-1 regulates mitochondrial function and promotes retinal ganglion cell survival under high glucose-induced oxidative stress

PurposeThis study aimed to investigate the antioxidative and neuroprotective effects of DJ-1 in mitigating retinal ganglion cell (RGC) damage induced by high glucose (HG).MethodsA diabetic mouse model and an HG-induced R28 cell model were employed for loss- and gain-of-function experiments. The expr...

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Main Authors: Hanhan Peng (Author), Haoyu Li (Author), Benteng Ma (Author), Xinyue Sun (Author), Baihua Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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