Local Administration of a Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Inflammatory Pain in Rats

• Main Authors: Koyo Ueda (Author), Munetaka Hirose (Author), Eri Murata (Author), Mayumi Takatori (Author), Masashi Ueda (Author), Hiroshi Ikeda (Author), Kenji Shigemi (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Novel agents that inhibit nerve growth factor signaling are required for the treatment of inflammatory pain. The present study investigated the effect of local administration of inhibitory peptide of TrkA (IPTRK3), a synthetic cell-penetrating peptide that antagonizes TrkA function, in complete Freu...