Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy

• Main Authors: Xiaohong Cen (Author), Baoqu Wang (Author), Yuqing Liang (Author), Yanlin Chen (Author), Yu Xiao (Author), Shaohua Du (Author), Kutty Selva Nandakumar (Author), Hang Yin (Author), Shuwen Liu (Author), Kui Cheng (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toll-like receptor 3 (TLR3), as an important pattern recognition receptor (PRR), dominates the innate and adaptive immunity regulating many acute and chronic inflammatory diseases. Atherosclerosis is proved as an inflammatory disease, and inflammatory events involved in the entire process of initiat...