In Vitro and In Vivo Antitumor Activity of Cucurbitacin C, a Novel Natural Product From Cucumber

• Main Authors: Dinglan Wu (Author), Zhu Wang (Author), Muqi Lin (Author), Yi Shang (Author), Fei Wang (Author), JiaYi Zhou (Author), Xiantong Zhang (Author), Xiaomin Luo (Author), Weiren Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cucurbitacin C (CuC), a novel analogue of triterpenoids cucurbitacins, confers a bitter taste in cucumber. Genes and signaling pathways responsive for biosynthesis of CuC have been identified in the recent years. In the present study, we explored the anti-cancer effects of CuC against human cancers...