Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways

• Principais autores: Shiri Li (Autor), Chie Takasu (Autor), Hien Lau (Autor), Lourdes Robles (Autor), Kelly Vo (Autor), Ted Farzaneh (Autor), Nosratola D. Vaziri (Autor), Michael J. Stamos (Autor), Hirohito Ichii (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2020-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium (DSS)-induced colitis via its potential antioxi...