A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B.
BACKGROUND:Leishmania donovani is a protozoan parasite, a primary causative agent of visceral leishmaniasis. Sterol produced via the mevalonate pathway, show differences in composition across biological kingdoms. The specific occurrence of Δ22-unsaturated sterols, containing a double bond at the C-2...
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| Main Authors: | , , , |
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| Format: | Book |
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Public Library of Science (PLoS),
2019-04-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |