Endoplasmic reticulum stress, degeneration of pancreatic islet β-cells, and therapeutic modulation of the unfolded protein response in diabetes

Background: Myriad challenges to the proper folding and structural maturation of secretory pathway client proteins in the endoplasmic reticulum (ER) - a condition referred to as "ER stress" - activate intracellular signaling pathways termed the unfolded protein response (UPR). Scope of rev...

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Main Authors: Rajarshi Ghosh (Author), Kevin Colon-Negron (Author), Feroz R. Papa (Author)
Format: Book
Published: Elsevier, 2019-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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