A novel zebrafish intestinal tumor model reveals a role for cyp7a1-dependent tumor-liver crosstalk in causing adverse effects on the host

• मुख्य लेखकों: Sora Enya (लेखक), Koichi Kawakami (लेखक), Yutaka Suzuki (लेखक), Shinpei Kawaoka (लेखक), Almut Schulze (लेखक), Mariia Yuneva (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2018-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The nature of host organs and genes that underlie tumor-induced physiological disruption on the host remains ill-defined. Here, we establish a novel zebrafish intestinal tumor model that is suitable for addressing this issue, and find that hepatic cyp7a1, the rate-limiting factor for synthesizing bi...