A novel zebrafish intestinal tumor model reveals a role for cyp7a1-dependent tumor-liver crosstalk in causing adverse effects on the host

• Asıl Yazarlar: Sora Enya (Yazar), Koichi Kawakami (Yazar), Yutaka Suzuki (Yazar), Shinpei Kawaoka (Yazar), Almut Schulze (Yazar), Mariia Yuneva (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2018-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The nature of host organs and genes that underlie tumor-induced physiological disruption on the host remains ill-defined. Here, we establish a novel zebrafish intestinal tumor model that is suitable for addressing this issue, and find that hepatic cyp7a1, the rate-limiting factor for synthesizing bi...