Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach

• Glavni autori: Katarzyna Jakimiuk (Autor), Suat Sari (Autor), Robert Milewski (Autor), Claudiu T. Supuran (Autor), Didem Şöhretoğlu (Autor), Michał Tomczyk (Autor)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Flavonoids are widely distributed in plants and constitute the most common polyphenolic phytoconstituents in the human diet. In this study, the in vitro inhibitory activity of 44 different flavonoids (1-44) against mushroom tyrosinase was studied, and an in silico study and type of inhibition for th...