Real-World Application of a Quantitative Systems Pharmacology (QSP) Model to Predict Potassium Concentrations from Electronic Health Records: A Pilot Case towards Prescribing Monitoring of Spironolactone

Quantitative systems pharmacology (QSP) models are rarely applied prospectively for decision-making in clinical practice. We therefore aimed to operationalize a QSP model for potas-sium homeostasis to predict potassium trajectories based on spironolactone administrations. For this purpose, we propos...

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Auteurs principaux: Andreas D. Meid (Auteur), Camilo Scherkl (Auteur), Michael Metzner (Auteur), David Czock (Auteur), Hanna M. Seidling (Auteur)
Format: Livre
Publié: MDPI AG, 2024-08-01T00:00:00Z.
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