Trans-acting aptazyme for conditional gene knockdown in eukaryotic cells

• Main Authors: Shan Zhou (Author), Meiyi Chen (Author), Yi Yuan (Author), Yan Xu (Author), Qinlin Pu (Author), Xilei Ai (Author), Shuai Liu (Author), Feng Du (Author), Xin Huang (Author), Juan Dong (Author), Xin Cui (Author), Zhuo Tang (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trans-acting hammerhead ribozyme inherits the advantages of being the smallest and best-characterized RNA-cleaving ribozyme, offering high modularity and the ability to cleave any desired sequence without the aid of any protein, as long as the target sequence contains a cleavage site. However, achie...