Sesquiterpene lactone derivatives of KSL-B targeting Arf1-Big1Sec7 interaction

• Główni autorzy: Sergio Ortiz (Autor), François Peurois (Autor), Euzébio Guimarães Barbosa (Autor), Mohamed Selkti (Autor), Pascale Lemoine (Autor), Jacqueline Cherfils (Autor), Raphaël Grougnet (Autor), Sabrina Boutefnouchet (Autor)
• Format: Książka
• Wydane: Elsevier, 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The GDP/GTP conformational change of Arf GTPase proteins by different guanine exchange factor GEFs proteins (Big1Sec7, ARNOSec7, Brag1Sec7, etc.), modulates important eukaryotes cell functions, such as secretion, endocytosis, phagocytosis, cytokinesis and cell adhesion. The overproduction and overac...