Irisin Attenuates Myocardial Ischemia/Reperfusion Injury and Improves Mitochondrial Function Through AMPK Pathway in Diabetic Mice

• Main Authors: Chao Xin (Author), Zheng Zhang (Author), Guojie Gao (Author), Liping Ding (Author), Chao Yang (Author), Chengzhu Wang (Author), Yanjun Liu (Author), Yufei Guo (Author), Xueqing Yang (Author), Lijuan Zhang (Author), Lina Zhang (Author), Yi Liu (Author), Zhitao Jin (Author), Ling Tao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AimsSeveral recent reports have shown irisin protects the heart against ischemia/reperfusion injury. However, the effect of irisin on I/R injury in diabetic mice has not been described. The present study was designed to investigate the role of irisin in myocardial ischemia-reperfusion (MI/R) injury...