Androgen receptor overexpression in prostate cancer in type 2 diabetes

• Main Authors: Stefan Zoltán Lutz (Author), Jörg Hennenlotter (Author), Marcus Oliver Scharpf (Author), Corinna Sailer (Author), Louise Fritsche (Author), Vera Schmid (Author), Konstantinos Kantartzis (Author), Robert Wagner (Author), Rainer Lehmann (Author), Lucia Berti (Author), Andreas Peter (Author), Harald Staiger (Author), Andreas Fritsche (Author), Falko Fend (Author), Tilman Todenhöfer (Author), Arnulf Stenzl (Author), Hans-Ulrich Häring (Author), Martin Heni (Author)
• Format: Book
• Published: Elsevier, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: While prostate cancer does not occur more often in men with diabetes, survival is markedly reduced in this patient group. Androgen signaling is a known and major driver for prostate cancer progression. Therefore, we analyzed major components of the androgen signaling chain and cell prolif...