Pre-mRNA processing factor 19 functions in DNA damage repair and radioresistance by modulating cyclin D1 in hepatocellular carcinoma

• Main Authors: Xiang-Nan Yu (Author), Guang-Cong Zhang (Author), Hai-Ning Liu (Author), Jin-Min Zhu (Author), Tao-Tao Liu (Author), Guang-Qi Song (Author), Ling Dong (Author), Jie Yin (Author), Xi-Zhong Shen (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pre-mRNA processing factor 19 (PRP19) is elevated in hepatocellular carcinoma (HCC); however, little is known about its function in DNA damage repair in HCC. In this study, analysis of The Cancer Genome Atlas data and our tumor models after ionizing radiation (IR) treatment indicated that increased...