Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation

• Main Authors: Stefan Poschner (Author), Alexandra Maier-Salamon (Author), Martin Zehl (Author), Judith Wackerlig (Author), Daniel Dobusch (Author), Anastasia Meshcheryakova (Author), Diana Mechtcheriakova (Author), Theresia Thalhammer (Author), Bettina Pachmann (Author), Walter Jäger (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of resveratrol (RES) in preventing breast cancer is controversial, as low concentrations may stimulate the proliferation of estrogen-receptor alpha positive (ERα+) breast cancer cells. As metabolism is the key factor in altering cellular estrogens, thereby influencing breast tumor growth, w...