Nobiletin acts as a potential anticancer agent against osteosarcoma by regulating ERK and AKT signaling pathways

• Hauptverfasser: Fu-Wen Niu (Verfasst von), Yong-Jie Zhang (Verfasst von), Kun Li (Verfasst von), Mao-Shu Zhang (Verfasst von)
• Format: Buch
• Veröffentlicht: Bangladesh Pharmacological Society, 2014-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The current study was aimed to evaluate the anti-proliferative activity of nobiletin, a flavonoid, on osteosarcoma cell line, SaOS-2. Furthermore, we attempted to investigate the signaling pathways involved in the cell growth inhibition mechanism. Upon exposure, nobiletin showed significant cell inh...