Senataxin Attenuates DNA Damage Response Activation and Suppresses Senescence

Oxidative stress, driven by reactive oxygen species (ROS) such as hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), induces DNA double-strand breaks (DSBs) that compromise genomic integrity. The DNA Damage Response (DDR), primarily mediated by ATM and ATR kinases, is crucial fo...

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Main Authors: Mingyang Li (Author), Genbao Shao (Author)
Format: Book
Published: MDPI AG, 2024-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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