Senataxin Attenuates DNA Damage Response Activation and Suppresses Senescence
Oxidative stress, driven by reactive oxygen species (ROS) such as hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), induces DNA double-strand breaks (DSBs) that compromise genomic integrity. The DNA Damage Response (DDR), primarily mediated by ATM and ATR kinases, is crucial fo...
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| Format: | Book |
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MDPI AG,
2024-10-01T00:00:00Z.
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