Integrated multi‐omics approach reveals the role of striated muscle preferentially expressed protein kinase in skeletal muscle including its relationship with myospryn complex

• Main Authors: Qifei Li (Author), Jasmine Lin (Author), Shiyu Luo (Author), Klaus Schmitz‐Abe (Author), Rohan Agrawal (Author), Melissa Meng (Author), Behzad Moghadaszadeh (Author), Alan H. Beggs (Author), Xiaoli Liu (Author), Mark A. Perrella (Author), Pankaj B. Agrawal (Author)
• Formato: Livro
• Publicado em: Wiley, 2024-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Autosomal‐recessive mutations in SPEG (striated muscle preferentially expressed protein kinase) have been linked to centronuclear myopathy with or without dilated cardiomyopathy (CNM5). Loss of SPEG is associated with defective triad formation, abnormal excitation-contraction cou...