Baicalin Enhanced Oral Bioavailability of Sorafenib in Rats by Inducing Intestine Absorption

• Main Authors: Jingyao Wei (Author), Ruijuan Liu (Author), Jiali Zhang (Author), Shuaibing Liu (Author), Dan Yan (Author), Xueqian Wen (Author), Xin Tian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Sorafenib (SOR) is an oral, potent, selective, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used as the first-line therapy for advanced hepatocellular carcinoma (HCC). Baicalin (BG) is used as adjuvant therapy for hepatitis, which accounts for the le...