The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation

• Main Authors: Johanes K. Kasim (Author), Jiwon Hong (Author), Anthony J. R. Hickey (Author), Anthony R. J. Phillips (Author), John A. Windsor (Author), Paul W. R. Harris (Author), Margaret A. Brimble (Author), Iman Kavianinia (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic ductal adenocarcinoma remains a highly debilitating condition with no effective disease-modifying interventions. In our search for natural products with promising anticancer activity, we identified the aminolipopeptide trichoderin A as a potential candidate. While it was initially isolate...