Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity

• Main Authors: Dickenson Anthony H (Author), Feng Guoping (Author), Kim Doo-Sik (Author), Matthews Elizabeth A (Author), Deng Ping (Author), Nguyen David (Author), Xu Zao C (Author), Luo Z David (Author)
• Format: Book
• Published: SAGE Publishing, 2009-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Nerve injury-induced expression of the spinal calcium channel alpha-2-delta-1 subunit (Ca_vα₂δ₁) has been shown to mediate behavioral hypersensitivity through a yet identified mechanism. We exami...