TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway

TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway

Objective: Obesity and type 2 diabetes (T2D) lead to various life-threatening diseases such as coronary heart disease, stroke, osteoarthritis, asthma, and neurodegeneration. Therefore, extensive research is ongoing to identify novel pathways that can be targeted in obesity/T2D. Deletion of the inosi...

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Main Authors: Sarbani Ghoshal (Author), Qingzhang Zhu (Author), Alice Asteian (Author), Hua Lin (Author), Haifei Xu (Author), Glen Ernst (Author), James C. Barrow (Author), Baoji Xu (Author), Michael D. Cameron (Author), Theodore M. Kamenecka (Author), Anutosh Chakraborty (Author)
Format: Book
Published: Elsevier, 2016-10-01T00:00:00Z.
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