Systematic Development and Characterization of Novel, High Drug-Loaded, Photostable, Curcumin Solid Lipid Nanoparticle Hydrogel for Wound Healing

• Main Authors: Simarjot Kaur Sandhu (Author), Suneel Kumar (Author), Jayant Raut (Author), Mandeep Singh (Author), Sandeep Kaur (Author), Garima Sharma (Author), Tomas L. Roldan (Author), Sonia Trehan (Author), Jennifer Holloway (Author), Gabriella Wahler (Author), Jeffrey D. Laskin (Author), Patrick J. Sinko (Author), Francois Berthiaume (Author), Bozena Michniak-Kohn (Author), Praveen Rishi (Author), Narayanan Ganesh (Author), Indu Pal Kaur (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid lipid nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure homogenization, without using organic solvents, were optimized using the Taguchi design followed by the central composite design. The...