Synthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects

• Main Authors: Arif Iftikhar Khan (Author), Shahzad Nazir (Author), Muhammad Nadeem ul Haque (Author), Rukesh Maharjan (Author), Farooq-Ahmad Khan (Author), Hamza Olleik (Author), Elise Courvoisier-Dezord (Author), Marc Maresca (Author), Farzana Shaheen (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antimicrobial peptides (AMPs) are a promising class of therapeutic alternatives with broad-spectrum activity against resistant pathogens. Small AMPs like temporin-SHa (<b>1</b>) and its first-generation analog [G10a]-SHa (<b>2</b>) possess notable efficacy against Gram-positi...