In vitro mechanistic study on mycophenolate mofetil drug interactions: effect of prednisone, cyclosporine, and others

• Main Authors: Junjun Mao (Author), Feifei Yu (Author), Weiwei Qin (Author), Guixian She (Author), Yi Rong (Author), Zhuohan Hu (Author), Mingkang Zhong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveThe metabolism- and transporter-based drug-drug interactions (DDIs) between mycophenolate mofetil (MMF) and co-administered medications may be key factors for the high individual variability in MMF exposure. This study systematically assessed the influence of co-medications on the mycopheno...