The olfactory receptor OR51E2 activates ERK1/2 through the Golgi-localized Gβγ-PI3Kγ-ARF1 pathway in prostate cancer cells

The olfactory receptor OR51E2 is ectopically expressed in prostate tissues and regulates prostate cancer progression, but its function and regulation in oncogenic mitogen-activate protein kinase (MAPK) activation are poorly defined. Here we demonstrate that β-ionone, an OR51E2 agonist, dose-dependen...

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Main Authors: Xin Xu (Author), Mostafa Khater (Author), Guangyu Wu (Author)
Format: Book
Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
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