Docetaxel-Loaded Disulfide Cross-Linked Nanoparticles Derived from Thiolated Sodium Alginate for Colon Cancer Drug Delivery

• Auteurs principaux: Hock Ing Chiu (Auteur), Asila Dinie Ayub (Auteur), Siti Nur Aishah Mat Yusuf (Auteur), Noorfatimah Yahaya (Auteur), Erazuliana Abd Kadir (Auteur), Vuanghao Lim (Auteur)
• Format: Livre
• Publié: MDPI AG, 2020-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

In this study, fluorescein-labelled wheat germ agglutinin (fWGA)-conjugated disulfide cross-linked sodium alginate nanoparticles were developed to specifically target docetaxel (DTX) to colon cancer cells. Different amounts of 3-mercaptopropionic acid (MPA) were covalently attached to sodium alginat...